The May issue of Health Affairs is centered on the use of precision medicine and genetic information to better diagnose and treat patients. It features real-world examples of how precision medicine works and proposes policy prescriptions advancing its implementation and impact in the United States and the world. Order your copy today! 

Here’s what else you’ll find inside:

ENTRY POINT

Patients Armed With Their Own Genetic Data Raise Tough Questions
Carina Storrs

OVERVIEW

Precision Medicine: From Science To Value
Geoffrey S. Ginsburg and Kathryn A. Phillips

RESEARCH ARTICLES

• Data Sharing For Precision Medicine: Policy Lessons And Future Directions
  Alessandro Blasimme, Marta Fadda, Manuel Schneider, and Effy Vayena
• Genetic Test Availability And Spending: Where Are We Now? Where Are We Going?
  Kathryn A. Phillips, Patricia A. Deverka, Gillian W. Hooker, and Michael P. Douglas
• Horizon Scan Of Clinical Laboratories Offering Pharmacogenetic Testing
  Susanne B. Haga and Ariel Kantor
• Precision Medicines Have Faster Approvals Based On Fewer And Smaller Trials Than Other Medicines
  Lisette Pregelj, Thomas J. Hwang, Damian C. Hine, Evan B. Siegel, Ross T. Barnard, Jonathan J. Darrow, and Aaron S. Kesselheim
• Evaluating The Impact Of The Orphan Drug Act’s Seven-Year Market Exclusivity Period
  Ameet Sarpatwari, Reed F. Beall, Abdurrahman Abdurrob, Mengdong He, and Aaron S. Kesselheim
• Assessing Medicare’s Approach To Covering New Drugs In Bundled Payments For Oncology
  L. Daniel Muldoon, Pamela M. Pelizzari, Kelsey A. Lang, Joe Vandigo, and Bruce S. Pyenson
• Strategies For Clinical Implementation: Precision Oncology At Three Distinct Institutions
  Lincoln D. Nadauld, James M. Ford, Daryl Pritchard, and Thomas Brown
• Patient-Centered Precision Health In A Learning Health Care System: Geisinger’s Genomic Medicine Experience
  Marc S. Williams, Adam H. Buchanan, F. Daniel Davis, W. Andrew Faucett, Miranda L. G. Hallquist, Joseph B. Leader, Christa L. Martin, Cara Z. McCormick, Michelle N. Meyer, Michael F. Murray, Alanna K. Rahm, Marci L. B. Schwartz, Amy C. Sturm, Jennifer K. Wagner, Janet L. Williams, Huntington F. Willard, and David H. Ledbetter
• Real-World Evidence In Support Of Precision Medicine: Clinico-Genomic Cancer Data As A Case Study
  Vineeta Agarwala, Sean Khozin, Gaurav Singal, Claire O’Connell, Deborah Kuk, Gerald Li, Anala Gossai, Vincent Miller, and Amy P. Abernethy
• Precision Medicine In Action: The Impact Of Ivacaftor On Cystic Fibrosis–Related Hospitalizations
  Lisa B. Feng, Scott D. Grosse, Ridgely Fisk Green, Aliza K. Fink, and Gregory S. Sawicki
• Lack Of Diversity In Genomic Databases Is A Barrier To Translating Precision Medicine Research Into Practice
  Latrice G. Landry, Nadya Ali, David R. Williams, Heidi L. Rehm, and Vence L. Bonham
• Characteristics Of Likely Precision Medicine Initiative Participants Drawn From A Large Blood Donor Population
  Cinnamon S. Bloss, Justin Stoler, Cynthia E. Schairer, Sara B. Rosenthal, Cynthia Cheung, Holly M. Rus, Jessica L. Block, Jiue-An “Jay” Yang, Doug Morton, Helen Bixenman, and David Wellis
• Views Of Primary Care Providers On Testing Patients For Genetic Risks For Common Chronic Diseases
  Diane Hauser, Aniwaa Owusu Obeng, Kezhen Fei, Michelle A. Ramos, and Carol R. Horowitz
• Delivery Of Cascade Screening For Hereditary Conditions: A Scoping Review Of The Literature
  Megan C. Roberts, W. David Dotson, Christopher S. DeVore, Erica M. Bednar, Deborah J. Bowen, Theodore G. Ganiats, Ridgely Fisk Green, Georgia M. Hurst, Alisdair R. Philp, Charité N. Ricker, Amy C. Sturm, Angela M. Trepanier, Janet L. Williams, Heather A. Zierhut, Katherine A. Wilemon, and Heather Hampel

DATAWATCH

PHARMACEUTICALS & MEDICAL TECHNOLOGY
Generic Price Competition For Specialty Drugs: Too Little, Too Late?
Ashley L. Cole and Stacie B. Dusetzina

COMMENTARY

Lessons Learned From A Study Of Genomics-Based Carrier Screening For Reproductive Decision Making
Benjamin S. Wilfond, Tia L. Kauffman, Gail P. Jarvik, Jacob A. Reiss, C. Sue Richards, Carmit McMullen, Marian Gilmore, Patricia Himes, Stephanie A. Kraft, Kathryn M. Porter, Jennifer L. Schneider, Sumit Punj, Michael C. Leo, John F. Dickerson, Frances L. Lynch, Elizabeth Clarke, Alan F. Rope, Kevin Lutz, and Katrina A. B. Goddard

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